Human ALCAM Protein, His Tag

Source : 

Human ALCAM, His Tag (CD6-H5228) is expressed from human 293 cells (HEK293). It contains AA Trp 28 - Ala 526 (Accession # Q13740-1).

 

Molecule : ALCAM

 

Synonyms : CD166,ALCAM,CD6L,KG-CAM,MEMD

 

Format : Powder

 

Category : Bio-Markers & CD Antigens

 

Accession : NP_001618.2

 

Storage : -20℃

 

Shipping condition : Powder,RT

 

Molecular Weight : 57.8 kDa

 

Characteristics :

This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 57.8 kDa. As a result of glycosylation, the protein migrates as 70-100 kDa under reducing (R) condition, and 66-100 kDa under non-reducing (NR) condition (SDS-P

 

Endotoxin Level : Less than 1.0 EU per μg by the LAL method.

 

Buffer : PBS, pH7.4

 

Description :

CD166 antigen is a 100-105 kD typeI transmembrane glycoprotein that is a member of the immunoglobulin superfamily of proteins, which is also known as Activated leukocyte cell adhesion molecule (ALCAM) in human, SC-1/DM-GRASP/BEN in the chicken, and KG-CAM in the rat. CD166 is a cell adhesion molecule that binds to CD6. CD166 involved in neurite extension by neurons via heterophilic and homophilic interactions.

 

References :

(1) Degen W.G., et al., 1998, Am. J. Pathol. 152:805-813.
(2) Skonier J.E., et al., 1996, Biochemistry 35:12287-12291.
(3) Bajorath J., et al., 1995, Protein Sci. 4:1644-1647.