Human ALCAM Protein, Fc Tag

Source : 

Human ALCAM, Fc Tag (CD6-H5259) is expressed from human 293 cells (HEK293). It contains AA Trp 28 - Ala 526 (Accession # NP_001618).

 

Molecule : ALCAM

 

Synonyms : CD166,ALCAM,CD6L,KG-CAM,MEMD

 

Format : Powder

 

Category : Bio-Markers & CD Antigens

 

Accession : NP_001618

 

Storage : -20℃

 

Shipping condition : Powder,RT

 

Molecular Weight : 82.6 kDa

 

Characteristics :

This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 82.6 kDa. The protein migrates as 95-116 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

 

Endotoxin Level : Less than 1.0 EU per μg by the LAL method.

 

Buffer : Tris with Glycine, Arginine and NaCl, pH7.5

 

Description :

CD166 antigen is a 100-105 kD typeI transmembrane glycoprotein that is a member of the immunoglobulin superfamily of proteins, which is also known as Activated leukocyte cell adhesion molecule (ALCAM) in human, SC-1/DM-GRASP/BEN in the chicken, and KG-CAM in the rat. CD166 is a cell adhesion molecule that binds to CD6. CD166 involved in neurite extension by neurons via heterophilic and homophilic interactions.

 

References :

(1) Degen W.G., et al., 1998, Am. J. Pathol. 152:805-813.
(2) Skonier J.E., et al., 1996, Biochemistry 35:12287-12291.
(3) Bajorath J., et al., 1995, Protein Sci. 4:1644-1647.