Human ACVR2B / ActivinR-IIB Protein (ECD, Fc Tag)

Species : Human

Synonyms : Activin RIIB,ActR-IIB,ACTRIIB,HTX4

Host : HEK293 Cells

Purity :> 97 % as determined by SDS-PAGE

Activity : 1. Measured by its ability to neutralize Activin-mediated inhibition on MPC11 cell proliferation. The ED50 for this effect is typically 0.02-0.1 ?g/mL in the presence of 10 ng/mL recombinant Activin A.
2. Measured by its binding ability in a functional ELISA. Immobilized Inhibin Human, Mouse, Rat, Cynomolgus, Rhesus Inhibin beta A/Activin A (Cat:10429-HNAH) at 2 £gg/ml (100 £gl/well) can bind Human ACVR2B hFc(Cat:10229-H02H), the EC50?of Human ACVR2B hFc is 12-60 ng/mL.