Hsp90 Antibody
- 貨號 Cat. No.
- 3098-100
- 規格 Size
- 100 µg
Description
pstrongAntibody Target :/strongHsp90/p
pbHost: /bMouse/p
pbAntibody Type: /bMonoclonal/p
pbIsotype: /bMouse IgG1/p
pbAntibody Form: /bAffinity Purified Antibody/p
pbImmunogen Sequence: /bAchlya ambisexualis Hsp90/p
pbAccession#: /bN/A/p
pbGene ID: /bN/A/p
pbAppearance: /bColorless liquid/p
pbConcentration: /b0.2 mg/ml/p
pbFormulation: /b100 micro;g (0.2 mg/ml) in PBS containing 1 mg/ml BSA, 50% glycerol, and 0.2% thimerosal./p
pbPurification: /bAffinity purified/p
pbSpecies Reactivity: /bhu/ms/rt/mk/ht/rb/bv/p
pbApplication: /bWB/IP/IF/p
pbApplication amp; Usage: /bWestern blot analysis (1-2micro;g/ml), immunoprecipitation (4-8 micro;g/ml) and Immunohistochemistry (10-20 micro;g/ml). However, the optimal conditions should be determined individually. The antibody recognizes a 90 kDa protein, corresponding to the apparent molecular weight of Hsp90 on SDS-PAGE immunoblots. This antibody detects both Hsp90 alpha and beta./p
pbStorage Temp.: /b-20 deg;C/p
pbShipping : /bgel pack/p
pbShelf Life: /b12 months/p
pbHandling: /bThe antibody solution should be gently mixed before use./p
pbBrief Background Descriptions: /bHsp90 (also known as Hsp82, Hsp83, or Hsp89), a 90 kDa protein, is the most abundant protein in the cytosolic fraction in many cell types. The high level of Hsp90 in many cell types suggests that Hsp90 may play a general role in the cell, but little is known about its general function. Hsp90 has no known enzymatic activity, and thus it has been presumed that Hsp90 may function through protein-protein interactions. Hsp90 exists in a dimeric form and has been observed to bind to several cellular proteins such as retro-virus kinases (PP60v-src), steroid receptors, heme-regulated protein kinase, actin and tubulin. In this regard, Hsp90, like Hsp70, may function as a ldquo;molecular chaperonerdquo;. Hsp90 exists as two isoforms referred to as Hsp86 and HSP84 in murine cells or Hsp90alpha; and Hsp90beta; in human cells./p
pbHost: /bMouse/p
pbAntibody Type: /bMonoclonal/p
pbIsotype: /bMouse IgG1/p
pbAntibody Form: /bAffinity Purified Antibody/p
pbImmunogen Sequence: /bAchlya ambisexualis Hsp90/p
pbAccession#: /bN/A/p
pbGene ID: /bN/A/p
pbAppearance: /bColorless liquid/p
pbConcentration: /b0.2 mg/ml/p
pbFormulation: /b100 micro;g (0.2 mg/ml) in PBS containing 1 mg/ml BSA, 50% glycerol, and 0.2% thimerosal./p
pbPurification: /bAffinity purified/p
pbSpecies Reactivity: /bhu/ms/rt/mk/ht/rb/bv/p
pbApplication: /bWB/IP/IF/p
pbApplication amp; Usage: /bWestern blot analysis (1-2micro;g/ml), immunoprecipitation (4-8 micro;g/ml) and Immunohistochemistry (10-20 micro;g/ml). However, the optimal conditions should be determined individually. The antibody recognizes a 90 kDa protein, corresponding to the apparent molecular weight of Hsp90 on SDS-PAGE immunoblots. This antibody detects both Hsp90 alpha and beta./p
pbStorage Temp.: /b-20 deg;C/p
pbShipping : /bgel pack/p
pbShelf Life: /b12 months/p
pbHandling: /bThe antibody solution should be gently mixed before use./p
pbBrief Background Descriptions: /bHsp90 (also known as Hsp82, Hsp83, or Hsp89), a 90 kDa protein, is the most abundant protein in the cytosolic fraction in many cell types. The high level of Hsp90 in many cell types suggests that Hsp90 may play a general role in the cell, but little is known about its general function. Hsp90 has no known enzymatic activity, and thus it has been presumed that Hsp90 may function through protein-protein interactions. Hsp90 exists in a dimeric form and has been observed to bind to several cellular proteins such as retro-virus kinases (PP60v-src), steroid receptors, heme-regulated protein kinase, actin and tubulin. In this regard, Hsp90, like Hsp70, may function as a ldquo;molecular chaperonerdquo;. Hsp90 exists as two isoforms referred to as Hsp86 and HSP84 in murine cells or Hsp90alpha; and Hsp90beta; in human cells./p