HMGA1 Antibody
Antibodies
- 貨號 Cat. No.
- 251402
- 規格 Size
- 0.1 mg
- 品牌 Brand
- Abbiotec
- Application 應用
- ELISA 、 IHC 、 WB
- Reactivity
- B 、 Human 、 Mouse 、 Rat
Description
High mobility group AT-hook protein 1 (HMGA1) binds preferentially to the minor groove of A+T rich regions in double stranded DNA. HMGA1 is involved in nucleosome phasing and in the 3'-end processing of mRNA transcripts. HMGA1 is also involved in the transcriptional regulation of genes containing, or in close proximity, to A+T-rich regions. A chromosomal aberration involving HMGA1 is found in pulmonary chondroid hamartoma.