Histone H3A Antibody

h1 class=titleHistone H3A Antibody/h1
div id=node-1516 class=node ntype-antibodiesRabbit Polyclonal
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h4Catalog Number/h4
pstrong250690/strong/p
h4Unit/h4
pstrong0.1 mg/strong/p
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Format/h4
pEach vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography./p
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h4Description/h4
pHistones are the core components of the nucleosomes that wrap and compact DNA into chromatin. DNA compacting limits accessibility to the cellular machineries which require DNA as template. Histones play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. The accessibility of DNA is regulated by post-translational modifications of histones such as acetylation, methylation and phosphorylation. The nucleosome is a histone octamer containing two molecules each of histone proteins H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers./p
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h4Product Citations/h4
pnbsp;/p
h4Recommended Products/h4
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h4Alternate Names/h4
pHistone H3.1; H3/a; HIST1H3A; H3FA/p
h4Accession No./h4
pa class=accession-link target=_blank href=http://www.expasy.ch/uniprot/P68431P68431/abr /
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h4Clonality/h4
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h4Antigen/h4
pnbsp;/p
pKLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human H3A./p
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h4Application Notes/h4
pnbsp;/p
pE: 1:500-1:1,000/p
pWB: 1:200-1:500/p
pIHC: 1:200-1:500/p
pstrongReacts with/strongnbsp; :H | M | R/p
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h4Storage/h4
pStore at -20deg;C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment./p
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