His6-UbcH3/Cdc34/UBE2R1
Proteins and Peptides
- 貨號 Cat. No.
- E2-610
- 規格 Size
- 50 µg, 100 µg
- 品牌 Brand
- Boston Biochem
Description
UbcH3 plays an essential role in the progression of cells from the G1 to S phase of the cell division cycle. One pathway (requiring Cdc34) initiates DNA replication by degrading a CDK (cyclin-dependent kinase) inhibitor. The second pathway, involves the anaphase-promoting complex (APC) initiates chromosome segregation and exit from mitosis by degrading anaphase inhibitors and mitotic cyclins.