His6-hHR6B
- 貨號 Cat. No.
- E2-613
- 規格 Size
- 50 μg 100 μg
- 品牌 Brand
- Boston Biochem
Description
His6-hHR6B
human recombinant
Product Information
50 μg 100 μg
X mg/ml (X μM) in 50 mM HEPES pH 7.8, 50 mM NaCl, 10% glycerol, 1 mM DTT. Concentration will vary with lot number.
20 kDa
> 95% by SDS-PAGE
Use & Storage
Typical enzyme concentration to support conjugation in vitro is 100 nM-1 μM depending on conditions.
Store at -80°C. Avoid multiple freeze/thaw cycles.
Catalog #: E2-613
His6-hHR6B
Product Source:
human recombinant
Also known as: His6-hHR6B (human Homolog of RAD6B)
The human HR6A and HR6B proteins share about 95% amino acid sequence identity with each other and about 70% with yeast counterparts, but notably lack the acidic C-terminal domain found in S. cerevisiae RAD6. The RAD6 pathway is essential to post-replication repair of DNA and damage-induced mutagenesis in eukaryotic cells. hHR6 protein expression is cell cycle regulated and function with RAD5 and RAD18 RING-Finger proteins. The human proteins function similar to the yeast homologs, and may have additional roles in chromatin remodeling and spermatogenesis. This protein has an N-terminal His6 tag, Accession NP_003328.
Product Information
Quantity:
50 μg 100 μg
Stock:
X mg/ml (X μM) in 50 mM HEPES pH 7.8, 50 mM NaCl, 10% glycerol, 1 mM DTT. Concentration will vary with lot number.
MW:
20 kDa
Purity:
> 95% by SDS-PAGE
Use & Storage
Use:
Typical enzyme concentration to support conjugation in vitro is 100 nM-1 μM depending on conditions.
Storage:
Store at -80°C. Avoid multiple freeze/thaw cycles.