Hirudin (2D7) Antibody

h1 class=titleHirudin (2D7) Antibody/h1
div id=node-256 class=node ntype-antibodiesMouse Monoclonal
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h4Catalog Number/h4
pstrong250211/strong/p
h4Unit/h4
pstrong0.1 mg /strong/p
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Format/h4
pEach vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-A/G affinity chromatography./p
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h4Description/h4
pHirudin is a highly effective and very specific anticoagulant which inhibits formation of fibrin and activation of factors V, VIII and XIII by forming irreversible, noncovalent 1:1 complexes with alpha-thrombin. Hirudin is used to treat heparin-induced thrombocytopenia (Refludan/Hoechst Marion Roussel). Hirudin is a 7 kDa protein naturally originating from the medical leech emHirudo medicinalis/em. This antibody recognizes hirudin under both native and reducing conditions in SDS-PAGE. The antibody binds to an epitope in the C-terminal region of hirudin with an affinity of 450 nM./p
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h4Product Citations/h4
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h4Recommended Products/h4
pa href=http://abbiotec.com/antibodies/hirudin-%284c10%29-antibody250295 Hirudin (4C10) Antibody/abr /
a href=http://abbiotec.com/antibodies/hirudin-%2812d8%29-antibody250294 Hirudin (12D8) Antibody/abr /
a href=http://abbiotec.com/antibodies/hirudin-%289b2%29-antibody250296 Hirudin (9B2) Antibody/abr /
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h4Alternate Names/h4
pHirudin variant-1; lepirudin/p
h4Accession No./h4
pa class=accession-link target=_blank href=http://kr.expasy.org/uniprot/P01050P01050/abr /
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h4Clonality/h4
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h4Antigen/h4
pnbsp;/p
pRecombinant hirudin (rHV2) produced in S. cerevisiae and coupled to diphteria toxoid./p
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h4Application Notes/h4
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pProduct Cat. No. 250211 reacts in western blot with hirudin in both reduced and non-reduced forms. Antibody binding to hirudin does not block interaction with alpha-thrombin.nbsp;/p
pE: 1:2,000br /
WB 1:500/p
pstrongReacts with/strongnbsp; :Other/p
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h4Storage/h4
pStore at 4deg;C. Product is guaranteed 6 months from the date of shipment./p
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