Hirudin (12D8) Antibody

h1 class=titleHirudin (12D8) Antibody/h1
div id=node-493 class=node ntype-antibodiesMouse Monoclonal
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h4Catalog Number/h4
pstrong250294/strong/p
h4Unit/h4
pstrong0.2 mg /strong/p
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Format/h4
pEach vial contains 0.2 mg IgG in 0.2 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-A/G affinity chromatography./p
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h4Description/h4
pHirudin is a highly effective and very specific anticoagulant which specifically inhibits formation of fibrin and activation of factors V, VIII and XIII by forming irreversible, noncovalent 1:1 complexes with a-thrombin. Hirudin is a 7 kDa protein naturally originating from the medical leech Hirudo medicinalis. The affinity (Kd) of this antibody for rHV2K47 is 3.5x10E-8 M. The antibody reacts with hirudin added to rabbit, rat, dog and monkey plasma./p
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h4Product Citations/h4
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h4Recommended Products/h4
pa href=http://abbiotec.com/antibodies/hirudin-%289b2%29-antibody250296 Hirudin (9B2) Antibody/abr /
a href=http://abbiotec.com/antibodies/hirudin-%284c10%29-antibody250295 Hirudin (4C10) Antibody/abr /
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h4Alternate Names/h4
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h4Accession No./h4
pa class=accession-link target=_blank href=http://www.expasy.org/uniprot/P01050P01050/abr /
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h4Clonality/h4
p12D8/p
h4Antigen/h4
pnbsp;/p
pRecombinant hirudin (rHV2) produced in S. cerevisiae and coupled to diphteria toxoid./p
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h4Application Notes/h4
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pProduct Cat. No. 250294 reacts in Western blot with full-length and C-terminal derivatized hirudins in both reduced and unreduced forms. Product Cat. No. 250294 is suitable as capture antibody in sandwich ELISA with Product Cat. No. 250296 as detection antibody on hirudin from plasma or urine. Binding of Product Cat. No. 250294 to hirudin inhibits the interaction with alpha-thrombin./p
pE: 1:4,000;/p
pWB: 1:500/p
pstrongReacts with/strongnbsp; :Other/p
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h4Storage/h4
pStore at 4deg;C. Product is guaranteed 6 months from the date of shipment./p
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