HER2 (K676) Antibody

貨號 Cat. No.
BS2463
規格 Size
100μg
品牌 Brand
Bioworld

Description

stock



Host: Rabbit


Reactivity: Human,Mouse,Rat


 



Product


1 mg/ml in Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.2.




Purification & Purity


The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).




Specificity


HER2 (K676) antibody detects endogenous levels of HER2 protein.




Applications (Recommended Dilutions)


WB: 1:500~1:1000 IHC: 1:50~1:200 IF: 1:50~1:200






Western Blot(WB)



Western blot (WB) analysis of HER2 (K676) antibody in extracts from 293 cells.





Immunohistochemistry (IHC)



Immunohistochemistry (IHC) analyzes of HER2 (K676) antibody in paraffin-embedded human breast carcinoma tissue.





Storage&Stability


Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.




Background


ErbB 2 is a receptor tyrosine kinase of the ErbB 2 family. It is closely related instructure to the epidermal growth factor receptor. ErbB 2 oncoprotein is detectable in a proportion of breast and other adenocarconomas, as well as transitional cell carcinomas. In the case of breast cancer, expression determined by immunohistochemistry has been shown to be associated with poor prognosis.


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