Her2 / ERBB2 Protein, Human, Recombinant (ECD, domain IV, His Tag)

Her2/ERBB2 Protein, Human, Recombinant (ECD, domain IV, His Tag): Product Information

Purity

> 85 % as determined by SDS-PAGE

Endotoxin

< 1.0 EU per μg protein as determined by the LAL method.

Activity

1.Measured by its binding ability in a functional ELISA.

2.Immobilized human ErbB2 (Cat:10004-H08H4) at 10μg/mL (100μL/well) can bind herceptin ,the EC50 of herceptin is 10-40ng/mL.

Protein Construction

A DNA sequence encoding the human ERBB2 (AAA75493.1) (Pro489-Cys630) was expressed with a polyhistidine tag at the C-terminus.

Accession#

AAA75493.1

Expressed Host

HEK293 Cells

Species

Human

Predicted N Terminal

Pro 489

Molecule Mass

The recombinant human ERBB2 consists of 153 amino acids and predicts a molecular mass of 17.1 kDa.