HCV-Core Antibody

h1 class=titleHCV-Core Antibody/h1
div id=node-1517 class=node ntype-antibodiesRabbit Polyclonal
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h4Catalog Number/h4
pstrong250683/strong/p
h4Unit/h4
pstrong0.1 mg/strong/p
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Format/h4
pEach vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography./p
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h4Description/h4
pThe p21 core protein from Hepatitis C virus (HCV) packages viral RNA to form a viral nucleocapsid and promotes virion budding . p21 modulates viral translation initiation and regulates many host cellular activities by interacting with HCV IRES and 40S ribosomal subunit. p21 also regulates host cellular functions that prevent the establishment of cellular antiviral state by blocking the interferon-alpha/beta (IFN-alpha/beta) and IFN-gamma signaling pathways and by inducing human STAT1 degradation. p21 plays an important role in the virus-mediated cell transformation leading to hepatocellular carcinomas./p
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h4Product Citations/h4
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h4Recommended Products/h4
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h4Alternate Names/h4
pGenome polyprotein Hepatitis C virus; Core protein p21; Core protein p19; HCV Capsid protein C/p
h4Accession No./h4
pa class=accession-link target=_blank href=http://www.expasy.ch/uniprot/P26664P26664/abr /
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h4Clonality/h4
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h4Antigen/h4
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pKLH-conjugated synthetic peptide encompassing a sequence within the N-term region of HCV p21 core protein./p
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h4Application Notes/h4
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pE: 1:500-1:1,000/p
pWB: 1:200-1:500/p
pIHC: 1:200-1:500/p
pstrongReacts with/strongnbsp; :Other/p
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h4Storage/h4
pStore at -20deg;C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment./p
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