HCK (3D12) Antibody

HCK (Hemopoietic cell kinase) is a protein-tyrosine kinase that is predominantly expressed in hemopoietic cell types. It may help to couple the Fc receptor to the activation of the respiratory burst. In addition, may play a role in neutrophil migration and in the degranulation of neutrophils. Alternate translation initiation site usage, including a non-AUG (CUG) codon, results in the production of two different isoforms, that have different subcellular localization.