HA-SUMO-1 Vinyl Sulfone

貨號 Cat. No.
UL-703
規格 Size
50 μg
品牌 Brand
Boston Biochem

Description

HA-SUMO-1 Vinyl Sulfone

Catalog #: UL-703




HA-SUMO-1 Vinyl Sulfone






Product Source: 

human recombinant



Also known as: HA-SUMO1-VS


This N-terminal HA-tagged SUMO is a potent, irreversible and specific inhibitor of SUMO-specific proteases (SENPs). This protein inhibits the hydrolysis of poly-SUMO chains on substrate proteins in vitro and thus enhances poly-SUMO chain accumulation. The HA peptide sequence (YPYDVPDYA) is derived from the influenza hemagglutinin protein. This epitope allows for the sensitive identification or purification of SENP activities since it is specifically recognized by anti-HA antibodies and/or anti-HA-agarose.


Product Information



Quantity: 

50 μg






Stock: 

X mg/ml (XμM) in 50 mM Hepes pH 7.0, 150 mMNaCl, 10 % glycerol. Concentration varies with Lot #.






MW: 

11.1 kDa






Purity: 

> 90%






Solubility: 

Soluble in DMSO up to 5 mg/ml. For best results, pellet dry compound prior to reconstitution.




 


Use & Storage



Use: 

Add directly to in vitro assay from the stock solution. Depending on conditions, typical concentrations to fully inhibit SENPs in vitro are 1-5 μM.






Storage: 

Store at -80°C. Avoid multiple freeze/thaw cycles.



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