h-NSE ELISA

Neuron Specific Enolase (2-phospho-D-glycerate
hydrolase) is an isoenzyme that belongs to the
enolase family (homo- and heterodimer constituted of
α, β and γ subunit) that is distingued from these by
the presence of the specific γγ heterodimer.
The clinical usefullness of hNSE like tumor marker is
compared to non small cell lunge cancer (NSCLC), to
neuroblastoma, to medullary carcinoma of the thyroid,
pancreatic islet cell tumor and to non neoplastic
condition of neuronal disease and cerebral trauma.
hNSE ELISA test cannot be used as a screening test
for neuroendocrine tumors, but may be used to follow
levels in established diagnosis.