GSK343
Chemical Compounds
- 貨號 Cat. No.
- A13114
- 規格 Size
- 5mg、10mg、25mg、50mg
- 品牌 Brand
- AdooQ
Description
GSK343 is a potent histone H3-lysine 27 (H3K27) methyltransferase EZH2 inhibitor (IC= 4 nM). Diplays 1000-fold selectivity for other HMTs except EZH1 (60-fold selectivity). GSK343 inhibits H3K27 methylation in HCC1806 cells with an IC of 200nM (measured by immunofluorescence).