GSK-LSD1 2HCl

貨號 Cat. No.
S7574-5mg
規格 Size
5mg
品牌 Brand
Selleckchem

Description



























Description



GSK-LSD1 2HCl is an irreversible, and selective LSD1 inhibitor with IC50 of 16 nM, > 1000 fold selective over other closely related FAD utilizing enzymes (i.e. LSD2, MAO-A, MAO-B).



Targets














LSD1 [1]


(Cell-free assay)



16 nM




In vitro



GSK-LSD1 induces gene expression changes in cancer cell lines with average EC50 of < 5 nM and inhibits cancer cell line growth with average EC50 of < 5 nM. [1]



Assay


















Methods



Test Index



PMID



Western blot



LSD1 / H3K4me2 ; 



29088714







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