GSK-3 Inhibitor, TWS119

Alternate Name/Synonyms: 3-[[6-(3-Aminophenyl)-1H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy]-phenol

Appearance: Slightly pink solid

Formulation: N/A

CAS Number: 601514-19-6

Molecular Formula: C₁₈H₁₄N₄O₂

Molecular Weight: 318.33

Purity: ≥95% by HPLC

Solubility: DMSO (20 mg/ml)

Storage Temp.: -20°C

Shipping Conditions: gel pack

Description: A potent inhibitor of GSK-3β (Glycogen synthase kinase-3β) (ICâ‚…â‚€ = 30 nM). At 400 nM, TWS119 induces neurogenesis in murine embryonic stem cells making it a useful tool to regulate stem cell self-renewal and differentiation.

Handling: Protect from air and light