Grim19 Polyclonal Ab
- 貨號 Cat. No.
- 3492-100
- 規格 Size
- 100 ug
Description
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pbHOST:/b Rabbit/p
pbIMMUNOGEN:/b Two synthetic peptides surrounding amino acid 19 and 55 of human GRIM-19/p
pbSPECIES REACTIVITY: /bhuman/p
pbFORMULATION: /b100 ug (0.5 mg/ml) immunoaffinity purified rabbit polyclonal antibody in phosphate-buffered saline (PBS) containing 30% glycerol, 0.5% BSA, and 0.01% thimerosal./p
pbSTORAGE CONDITIONS: /bStore at -20oC. For long term storage, aliquot and freeze at -70oC. Avoid repeated freeze/defrost cycles./p
pbBACKGROUND: /bMitochondrial NADH:ubiquinone oxidoreductase (complex I) catalyzes the first step in the electron transport chain, the oxidation of NADH to NAD+ coupled to proton translocation across the inner mitochondrial membrane. GRIM-19 is a component of the complex I and is a product of a cell death regulatory gene induced by interferon-ß and retinoic acid. GRIM-19 has previously been detected in HeLa cells, predominantly in the nucleus, though punctate staining of the cytoplasm was also observed./p
pbSPECIFICITY: /bThe antibody recognizes 16 kDa GRIM-19 of human origin. Reactivity to other species has not been tested./p
pbAPPLICATION: /bThe antibody has been used in Western blotting (0.5-4 ug/ml). However, the optimal concentrations should be determined individually./p
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pbHOST:/b Rabbit/p
pbIMMUNOGEN:/b Two synthetic peptides surrounding amino acid 19 and 55 of human GRIM-19/p
pbSPECIES REACTIVITY: /bhuman/p
pbFORMULATION: /b100 ug (0.5 mg/ml) immunoaffinity purified rabbit polyclonal antibody in phosphate-buffered saline (PBS) containing 30% glycerol, 0.5% BSA, and 0.01% thimerosal./p
pbSTORAGE CONDITIONS: /bStore at -20oC. For long term storage, aliquot and freeze at -70oC. Avoid repeated freeze/defrost cycles./p
pbBACKGROUND: /bMitochondrial NADH:ubiquinone oxidoreductase (complex I) catalyzes the first step in the electron transport chain, the oxidation of NADH to NAD+ coupled to proton translocation across the inner mitochondrial membrane. GRIM-19 is a component of the complex I and is a product of a cell death regulatory gene induced by interferon-ß and retinoic acid. GRIM-19 has previously been detected in HeLa cells, predominantly in the nucleus, though punctate staining of the cytoplasm was also observed./p
pbSPECIFICITY: /bThe antibody recognizes 16 kDa GRIM-19 of human origin. Reactivity to other species has not been tested./p
pbAPPLICATION: /bThe antibody has been used in Western blotting (0.5-4 ug/ml). However, the optimal concentrations should be determined individually./p