Granzyme B Monoclonal Antibody
- 貨號 Cat. No.
- 3073-100
- 規格 Size
- 100 ug
Description
pimg src=http://www.biovision.com/Merchant2/graphics/00000001/antibody-stock-miva.jpg alt= /nbsp;/p
pfont size=2strongHOST: /strongMousebr /
br /
strongISOTYPE: /strongIgG1br /
br /
strongCLONE: /strongB18.1br /
br /
strongIMMUNOGEN: /strongHuman recombinant granzyme B (a.a. 7-227) br /
br /
strongSPECIES REACTIVITY: /strongHuman br /
br /
strongFORMULATION: /strongbr /
100 ug (0.5 mg/ml) in PBS containing 1 mg/ml BSA, 1.5 mM sodium azide and 50% glycerol.br /
br /
strongSTORAGE: /strongbr /
Store at -20oC. For long term storage, aliquot and refreeze at -70oC. Avoid repeated freeze/thaw cycles.br /
br /
strongDESCRIPTION:/strong br /
Granzyme B is a 27 kDa serine protease stored in granules of activated cytotoxic T cells and NK cells. Upon target cell contact, granzyme B is directionally exocytosed and assisted by perforin, enters the target cell. With its unique substrate specificity (granzyme B cleaves after Asp), granzyme B processes and activates various pro-caspases thereby inducing apoptosis in the target cell. br /
br /
strongAPPLICATIONS: /strongbr /
Western blot, immunoprecipitation, flow cytometry and Immunohistochemistry. However, the optimal conditions should be determined individually. br /
br /
strongNOTE: For research use only! Not to be used in humans.br /
/strong/font/p
pfont size=2strongHOST: /strongMousebr /
br /
strongISOTYPE: /strongIgG1br /
br /
strongCLONE: /strongB18.1br /
br /
strongIMMUNOGEN: /strongHuman recombinant granzyme B (a.a. 7-227) br /
br /
strongSPECIES REACTIVITY: /strongHuman br /
br /
strongFORMULATION: /strongbr /
100 ug (0.5 mg/ml) in PBS containing 1 mg/ml BSA, 1.5 mM sodium azide and 50% glycerol.br /
br /
strongSTORAGE: /strongbr /
Store at -20oC. For long term storage, aliquot and refreeze at -70oC. Avoid repeated freeze/thaw cycles.br /
br /
strongDESCRIPTION:/strong br /
Granzyme B is a 27 kDa serine protease stored in granules of activated cytotoxic T cells and NK cells. Upon target cell contact, granzyme B is directionally exocytosed and assisted by perforin, enters the target cell. With its unique substrate specificity (granzyme B cleaves after Asp), granzyme B processes and activates various pro-caspases thereby inducing apoptosis in the target cell. br /
br /
strongAPPLICATIONS: /strongbr /
Western blot, immunoprecipitation, flow cytometry and Immunohistochemistry. However, the optimal conditions should be determined individually. br /
br /
strongNOTE: For research use only! Not to be used in humans.br /
/strong/font/p