Granzyme B Monoclonal Ab
- 貨號 Cat. No.
- 3173-100
- 規格 Size
- 100 ug
Description
pimg src=http://www.biovision.com/Merchant2/graphics/00000001/antibody-stock-miva.jpg alt= /nbsp;/p
pfont size=2 /font/p
pbHOST:/b Mouse/p
pbISOTYPE:/b IgG2a/p
pbCLONE:/b O2C5/F5/p
pbIMMUNOGEN:/b human Granzyme B/p
pbSPECIES REACTIVITY:/b Human, rat ANTIBODY/p
pbFORMULATION:/b Concentrated mouse tissue culture supernatant (1 mg/ml) in PBS containing 30% glycerol, 0.1% BSA and 0.01% thimerosal./p
pbSTORAGE CONDITIONS:/b Store at -20oC. For long term storage, aliquot and refreeze at -70oC. Avoid freeze/defrost cycles./p
pThe Lytic enzymes of cytotoxic lymphocytes seem to be contained within lysosome-like granules found in the cytoplasm. These granules contain perforin, a membrane pore-forming protein, and a family of serine proteases (granzymes). Granzyme B, a 32 kDa protein, is a serine Aspase associated with the granules of Natural Killer (NK) cells. Granzyme B seems to be able to elicit cell death, perhaps by activating an endogenous pathway of programmed cell death./p
pbDESCRIPTION:/b/p
pbSPECIFICITY:/b The antibody detects 35 kDa human and rat granzyme B. The antibody does not bind to Granzyme H, Granzyme A, or mouse Granzyme B./p
pbAPPLICATION AND USAGE:/b The antibody can be used for Western blot analysis (0.5-4 ug/ml) and immunoprecipitation. However, the optimal conditions should be determined individually./p
pbNOTE:/b/p
pbFOR RESEARCH USE ONLY! NOT TO BE USED IN HUMANS./b/p
pfont size=2 /font/p
pbHOST:/b Mouse/p
pbISOTYPE:/b IgG2a/p
pbCLONE:/b O2C5/F5/p
pbIMMUNOGEN:/b human Granzyme B/p
pbSPECIES REACTIVITY:/b Human, rat ANTIBODY/p
pbFORMULATION:/b Concentrated mouse tissue culture supernatant (1 mg/ml) in PBS containing 30% glycerol, 0.1% BSA and 0.01% thimerosal./p
pbSTORAGE CONDITIONS:/b Store at -20oC. For long term storage, aliquot and refreeze at -70oC. Avoid freeze/defrost cycles./p
pThe Lytic enzymes of cytotoxic lymphocytes seem to be contained within lysosome-like granules found in the cytoplasm. These granules contain perforin, a membrane pore-forming protein, and a family of serine proteases (granzymes). Granzyme B, a 32 kDa protein, is a serine Aspase associated with the granules of Natural Killer (NK) cells. Granzyme B seems to be able to elicit cell death, perhaps by activating an endogenous pathway of programmed cell death./p
pbDESCRIPTION:/b/p
pbSPECIFICITY:/b The antibody detects 35 kDa human and rat granzyme B. The antibody does not bind to Granzyme H, Granzyme A, or mouse Granzyme B./p
pbAPPLICATION AND USAGE:/b The antibody can be used for Western blot analysis (0.5-4 ug/ml) and immunoprecipitation. However, the optimal conditions should be determined individually./p
pbNOTE:/b/p
pbFOR RESEARCH USE ONLY! NOT TO BE USED IN HUMANS./b/p