Goat anti-TRPC6 Antibody

Antibodies

貨號 Cat. No.
G-1878-100
規格 Size
100 μg
品牌 Brand
Biosensis
Application 應用
Pep-ELISA, WB, FC
Reactivity
Expected to react with Dog 、 Human 、 pig and Cow
Host
Goat
Clonality
Polyclonal

Description




ZZZZ_Status (Active, Disc) : Active


 

AA_Supplier Name : Biosensis


 

Alternative_Name (Other Names) :


TRPC6; transient receptor potential cation channel, subfamily C, member 6; HGNC:12338; TRP6; transient receptor potential channel 6; FLJ11098; FLJ14863; FSGS2; TRP6


 

Antibody_Isotype
(Antibody only) :


 

Application_Details :


Western Blot: Approx 100kDa band observed in lysates of cell line A549 (calculated MW of 106kDa according to NP_004612.2). Preliminary experiments also showed 100kDa in Human Lung lysates and in lysates of cell line HEK293.This molecular weight is routinely observed by other sources. Recommended concentration: 0.3-1µg/ml. Primary incubation 1 hour at room temperature.Flow Cytometry: Flow cytometric analysis of A549 cells. Recommended concentration: 10ug/ml.Peptide ELISA: antibody detection limit dilution 1:2000.


 

Background_Info :


 

Clone_Name
(AB only, monoclonals) :


 

Datasheet_Link :


 

Description (Long Description) : 


Thought to form a receptor-activated non-selective calcium permeant cation channel (PubMed:19936226, PubMed:23291369). Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Activated by diacylglycerol (DAG) in a membrane-delimited fashion, independently of protein kinase C (PubMed:26892346). Seems not to be activated by intracellular calcium store depletion (uniprot).

 

Expiry_Date : 


12 months after purchase if unopened.

 

Format (Form) : 


Liquid antibody. Supplied at 0.5 mg/mL in Tris saline, 0.02% sodium azide, pH 7.3 with 0.5% bovine serum albumin.

 

Immunogen (Antigen) :A synthetic peptide consisting of amino acids, C-EKLSMEPNQEETN


 

Kit_Components :


 

MSDS (File name) :


 



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