Goat anti-Tet2 (mouse) Antibody

ZZZZ_Status (Active, Disc) : Active

 

AA_Supplier Name : Biosensis

 

Alternative_Name (Other Names) :

Tet2, tet oncogene family member 2, Ayu17-449, E130014J05Rik, MGC37385, mKIAA1546, methylcytosine dioxygenase TET2, probable methylcytosine dioxygenase TET2, tet oncogene 2, Ayu17-449, E130014J05Rik, methylcytosine dioxygenase TET2, MGC37385, mKIAA1546, probable methylcytosine dioxygenaseTET2, tet oncogene 2, tet oncogene family member 2, Tet2

 

Antibody_Isotype
(Antibody only) :

 

Application_Details :

Western Blot: Preliminary experiments gave an approx 200kDa band in Mouse Kidney and stomach lysate, after 1µg/ml antibody staining. (calculated MWt of 212kDa according to NP_001035490.2. Primary incubation 1 hour at room temperature.Flow Cytometry: Flow cytometric analysis of NIH3T3 cells. Recommended concentration: 10ug/ml.Peptide ELISA: antibody detection limit dilution 1:16000.

 

Background_Info :

 

Clone_Name
(AB only, monoclonals) :

 

Datasheet_Link :

 

Description (Long Description) : 

Dioxygenase that catalyzes the conversion of the modified genomic base 5-methylcytosine (5mC) into 5-hydroxymethylcytosine (5hmC) and plays a key role in active DNA demethylation. In addition to its role in DNA demethylation, also involved in the recruitment of the O-GlcNAc transferase OGT to CpG-rich transcription start sites of active genes, thereby promoting histone H2B GlcNAcylation by OGT (Uniprot).

 

Expiry_Date : 

12 months after purchase if unopened.

 

Format (Form) : 

Liquid antibody. Supplied at 0.5 mg/mL in Tris saline, 0.02% sodium azide, pH 7.3 with 0.5% bovine serum albumin.

 

Immunogen (Antigen) :A synthetic peptide consisting of amino acids, C-QPSLTSAQINFSQT

 

Kit_Components :

 

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