Goat anti-OAZ Antibody

ZZZZ_Status (Active, Disc) : Active

 

AA_Supplier Name : Biosensis

 

Alternative_Name (Other Names) :

ZNF423 ; zinc finger protein 423 ; Ebfaz; KIAA0760; MGC138520; MGC138522; OAZ; Roaz; ZFP423; Zfp104; OLF-1/EBF associated zinc finger; Smad- and Olf-interacting zinc finger protein; early B-cell factor associated zinc finger protein

 

Antibody_Isotype
(Antibody only) :

 

Application_Details :

Immunofluorescence: Strong expression of the protein seen in the nuclei of A431 cells. Recommended concentration: 10µg/ml.

Flow Cytometry: Flow cytometric analysis of Kelly cells. Recommended concentration: 10ug/ml.

Peptide ELISA: antibody detection limit dilution 1:2000.

 

Background_Info :

 

Clone_Name
(AB only, monoclonals) :

 

Datasheet_Link :

 

Description (Long Description) : 

Transcription factor that can both act as an activator or a repressor depending on the context. Plays a central role in BMP signaling and olfactory neurogenesis. Associates with SMADs in response to BMP2 leading to activate transcription of BMP target genes. Acts as a transcriptional repressor via its interaction with EBF1, a transcription factor involved in terminal olfactory receptor neurons differentiation; this interaction preventing EBF1 to bind DNA and activate olfactory-specific genes. Involved in olfactory neurogenesis by participating in a developmental switch that regulates the transition from differentiation to maturation in olfactory receptor neurons. Controls proliferation and differentiation of neural precursors in cerebellar vermis formation (Uniprot).

 

Expiry_Date : 

12 months after purchase if unopened.

 

Format (Form) : 

Liquid antibody. Supplied at 0.5 mg/mL in Tris saline, 0.02% sodium azide, pH 7.3 with 0.5% bovine serum albumin.

 

Immunogen (Antigen) :A synthetic peptide consisting of amino acids, EPECDQKTSRALEDR

 

Kit_Components :

 

MSDS (File name) :