Goat anti-BLNK / SLP-65 Antibody

ZZZZ_Status (Active, Disc) : Active

 

AA_Supplier Name : Biosensis

 

Alternative_Name (Other Names) :

BLNK; SLP-65; B-cell linker; BASH; BLNK-s; Ly57; MGC111051; SLP65; B cell linker protein; B-cell adapter containing a SH2 domain protein; B-cell adapter containing a Src homology 2 domain protein; OTTHUMP00000020167; Src homology 2 domain-containing leukocyte protein of 65 kDa; BLNK-S; LY57; OTTHUMP00000020168

 

Antibody_Isotype
(Antibody only) :

 

Application_Details :

Western Blot: Approx 70-75kDa band observed in lysates of cell line Daudi (calculated MW of 50.5kDa according to NP_037446.1). This molecular weight is routinely observed by other sources. Recommended concentration 0.3-1µg/ml. Primary incubation 1 hour at room temperature.Immunofluorescence: Strong expression of the protein seen in the membranes of HepG2 cells. Recommended concentration: 10µg/ml.

Flow Cytometry: Flow cytometric analysis of Daudi cells. Recommended concentration: 10ug/ml.

Peptide ELISA: antibody detection limit dilution 1:32000.

 

Background_Info :

 

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(AB only, monoclonals) :

 

Datasheet_Link :

 

Description (Long Description) : 

Functions as a central linker protein, downstream of the B-cell receptor (BCR), bridging the SYK kinase to a multitude of signaling pathways and regulating biological outcomes of B-cell function and development. Plays a role in the activation of ERK/EPHB2, MAP kinase p38 and JNK. Modulates AP1 activation (Uniprot)

 

Expiry_Date : 

12 months after purchase if unopened.

 

Format (Form) : 

Liquid antibody. Supplied at 0.5 mg/mL in Tris saline, 0.02% sodium azide, pH 7.3 with 0.5% bovine serum albumin.

 

Immunogen (Antigen) :A synthetic peptide consisting of amino acids, C-KDSTRLKYAVKVS

 

Kit_Components :

 

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