Go 6976
- 貨號 Cat. No.
- 1711-500
- 規格 Size
- 500 µg
Description
Alternate Name/Synonyms: 5,6,7,13-Tetrahydro-13-methyl-5-oxo-12H-indolo[2,3-a]py- rrolo[3,4-c]carbazole-12-propanenitrile; Go6976; PD 406976
Appearance: Off-white to yellow solid
Formulation: N/A
CAS Number: 136194-77-9
Molecular Formula: Câ‚‚â‚„Hâ‚₈Nâ‚„O
Molecular Weight: 378.43
Purity: ≥99% by HPLC
Solubility: DMSO
Storage Temp.: -20°C
Shipping Conditions: gel pack
Description: Cell-permeable. A potent protein kinase C (PKC) inhibitor (ICâ‚…â‚€ = 7.9 nM). In vitro, discriminates between Ca²âº-dependent and -independent isoforms of PKC; selectively inhibits PKCα and PKCβ1 (ICâ‚…â‚€ values are 2.3 and 6.2 nM respectively) but does not inhibit the activity of PKCδ, -ε, or -ζ (ICâ‚…â‚€ > 3µM).
Handling: Protect from air and light