Glypican-3 Antibody

Glypican-3 (GPC3) is a cell surface proteoglycan that bears heparan sulfate. GPC3 is likely involved in the modulation of growth in the predominantly mesodermal tissues and organs. Defects in GPC3 are the cause of pre- and postnatal overgrowth (gigantism, Simpson-Golabi-Behmel syndrome).