Glutamate Decarboxylase Antibody

Antibodies

貨號 Cat. No.
250502
規格 Size
0.1 mg
品牌 Brand
Abbiotec
Application 應用
ELISA 、 WB
Reactivity
B 、 Canine 、 Human 、 Mouse 、 Rat

Description

GAD65, an autoantigen in type I diabetes, is transiently activated in response to the demand for extra GABA in neurotransmission, and cycles between an active holo form and an inactive apo form. An inherently mobile catalytic loop promotes a side reaction that results in cofactor release and GAD65 autoactivation.

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