Glutamate Decarboxylase Antibody
Antibodies
- 貨號 Cat. No.
- 250502
- 規格 Size
- 0.1 mg
- 品牌 Brand
- Abbiotec
- Application 應用
- ELISA 、 WB
- Reactivity
- B 、 Canine 、 Human 、 Mouse 、 Rat
Description
GAD65, an autoantigen in type I diabetes, is transiently activated in response to the demand for extra GABA in neurotransmission, and cycles between an active holo form and an inactive apo form. An inherently mobile catalytic loop promotes a side reaction that results in cofactor release and GAD65 autoactivation.