Glucagon-Like Peptide 2

Glucagon-like peptide 2 (GLP-2) plays a key role in nutrient homeostasis, intestinal glucose transport and mucosal permeability. Glucagon, secreted in the A cells of the islets of Langherans, plays a key role in glucose metabolism and homeostasis. Proglucagon is processed in glucagon, GLP-1, GLP-2, glicentin and oxyntomodulin depending on tissue. Glucagon is used to treat severe hypoglycemia in insulin-dependent diabetics under the names Glucagon (Eli Lilly) and GlucaGen or Glucagon Novo Nordisk (Novo Nordisk).