GLP-1 (A3) Antibody

h1 class=titleGLP-1 (A3) Antibody/h1
div id=node-1730 class=node ntype-antibodiesMouse Monoclonal
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h4Catalog Number/h4
pstrong251102/strong/p
h4Unit/h4
pstrong0.2 mg /strong/p
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Format/h4
pEach vial contains 0.2 mg IgG in 0.2 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-A/G affinity chromatography./p
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h4Description/h4
pGlucagon-like peptide 1 (9-36)amide and GLP-1 (9-37) are processed forms of GLP-1 that results from the rapid degradation of the active forms of the peptide (GLP-1(7-36)amide and GLP-1(7-37)) by the enzyme dipeptidyl peptidase-IV (DPP-IV, CD26, adenosine deaminase binding protein). GLP-1 is a peptide hormone of the glucagon family, produced by the L cells of the intestinal mucosa from the same prohormone as glucagon. The active forms are potent stimulators of glucose-dependent insulin secretion. The sequence of GLP-1 is fully conserved in all mammalian species examined so far. This antibody binds to the free N-terminus of GLP-1(9-36)amide and GLP-1 (9-37)./p
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h4Product Citations/h4
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h4Recommended Products/h4
pa href=http://abbiotec.com/antibodies/glp-1-%288g9%29-antibody250364 GLP-1 (8G9) Antibody/abr /
a href=http://abbiotec.com/antibodies/glp-1-%284f3%29-antibody250366 GLP-1 (4F3) Antibody/abr /
a href=http://abbiotec.com/antibodies/glp-1-%285b10%29-antibody250367 GLP-1 (5B10) Antibody/abr /
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h4Alternate Names/h4
pGlucagon-like peptide 1; GLP-1; Glucagon; GCG; GLP-1(9-36)amide; GLP-1(9-37)/p
h4Accession No./h4
pa class=accession-link target=_blank href=http://www.expasy.ch/uniprot/P01275P01275/abr /
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h4Clonality/h4
pnbsp;/p
h4Antigen/h4
pnbsp;/p
pSynthetic [Cys19]-GLP-1(9-18) coupled to carrier/p
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h4Application Notes/h4
pnbsp;/p
pProduct Cat. No. 251102 binds to the free N-terminus of GLP-1 (9-36)amide and GLP-1 (9-37) in solution. The antibody binds to GLP-1(9-36)amide (1 ug/ml) coated directly onto the microtiter well. Product Cat. No. 251102 as capture antibody binds to the N-terminus of GLP-1 (9-36)amide in a different manner that product Cat. No. 251103 does. Product Cat. No. 251102 can be used in a sandwich ELISA as capture antibody with product Cat. No. 251104 (biotinylated Cat. No. 250364) as detection antibody. Cross-reactivity of Cat. No. 251102 for GLP-1(7-36)amide is estimated at lt;3% based on inhibition ELISA./p
pE: 1:6,000/p
pstrongReacts with/strongnbsp; :Mk | H | M | R | Other/p
pnbsp;/p
h4Storage/h4
pStore at 4deg;C. Product is guaranteed 6 months from the date of shipment./p
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