GLP-1 (8G9) Antibody

Glucagon-like peptide 1 (7-36)amide (GLP-1 (7-36)amide) is the principal active form of GLP-1, the other being GLP-1 (7-37). GLP-1 is a peptide hormone of the glucagon family, produced by the L cells of the intestinal mucosa from the same prohormone as glucagon. The active forms are potent stimulators of glucose-dependent insulin secretion. The sequence of GLP-1 is fully conserved in all mammalian species examined so far. This antibody is specific for the amidated C terminus of the peptide and does not react with GLP-1 (7-37). This antibody can be used in sandwich ELISA for detecting active GLP-1 or total amidated GLP-1.