GDNF Antibody
- 貨號 Cat. No.
- 5098-100
- 規格 Size
- 100 µg
Description
p
pnbsp;/p
nbsp;strongAntibody Target :/strongGDNF/p
pbHost: /bRabbit/p
pbAntibody Type: /bPolyclonal/p
pbIsotype: /bRabbit IgG/p
pbAntibody Form: /bAffinity Purified Antibody/p
pbImmunogen Sequence: /bSynthetic peptide surrounding amino acid 195 of mouse GDNF/p
pbAccession#: /bBAA08660/p
pbGene ID: /b14573/p
pbAppearance: /bColorless liquid/p
pbConcentration: /b0.2 mg/ml/p
pbFormulation: /b100 micro;g (0.2 mg/ml) protein A affinity purified rabbit polyclonal antibody in phosphate-buffered saline (PBS) containing 30% glycerol, 0.5% BSA, and 0.01% thimerosal./p
pbPurification: /bAffinity purified/p
pbSpecies Reactivity: /bhu/ms/rt/p
pbApplication: /bWB/IP/IHC/p
pbApplication amp; Usage: /bWestern blotting (0.5-4 micro;g/ml). Based on researcherrsquo;s feedback, the antibody also works in immunoprecipitation (10-20 micro;g/ml), and immunohistochemistry (10-20 micro;g/ml). However, the optimal concentrations should be determined individually. The antibody recognizes GDNF of human, mouse, and rat origins. Jurkat cell lysate can be used as a positive control./p
pbStorage Temp.: /b-20 deg;C/p
pbShipping : /bgel pack/p
pbShelf Life: /b12 months/p
pbHandling: /bThe antibody solution should be gently mixed before use./p
pbBrief Background Descriptions: /bGlial cell line-derived neurotrophic factor (GDNF) has been identified as a potent neurotrophic factor that enhances survival of midbrain dopaminergic neurons. GDNF is a glycosylated, disulfide-bonded homodimer. It promotes the survival and morphological differentiation of dopaminergic neurons and increases their high-affinity dopamine uptake. On the basis of these findings, it has been suggested that GDNF may play a role in the treatment of Parkinsonrsquo;s disease, which is marked by progressive degeneration of midbrain dopaminergic neurons./p
pnbsp;/p
nbsp;strongAntibody Target :/strongGDNF/p
pbHost: /bRabbit/p
pbAntibody Type: /bPolyclonal/p
pbIsotype: /bRabbit IgG/p
pbAntibody Form: /bAffinity Purified Antibody/p
pbImmunogen Sequence: /bSynthetic peptide surrounding amino acid 195 of mouse GDNF/p
pbAccession#: /bBAA08660/p
pbGene ID: /b14573/p
pbAppearance: /bColorless liquid/p
pbConcentration: /b0.2 mg/ml/p
pbFormulation: /b100 micro;g (0.2 mg/ml) protein A affinity purified rabbit polyclonal antibody in phosphate-buffered saline (PBS) containing 30% glycerol, 0.5% BSA, and 0.01% thimerosal./p
pbPurification: /bAffinity purified/p
pbSpecies Reactivity: /bhu/ms/rt/p
pbApplication: /bWB/IP/IHC/p
pbApplication amp; Usage: /bWestern blotting (0.5-4 micro;g/ml). Based on researcherrsquo;s feedback, the antibody also works in immunoprecipitation (10-20 micro;g/ml), and immunohistochemistry (10-20 micro;g/ml). However, the optimal concentrations should be determined individually. The antibody recognizes GDNF of human, mouse, and rat origins. Jurkat cell lysate can be used as a positive control./p
pbStorage Temp.: /b-20 deg;C/p
pbShipping : /bgel pack/p
pbShelf Life: /b12 months/p
pbHandling: /bThe antibody solution should be gently mixed before use./p
pbBrief Background Descriptions: /bGlial cell line-derived neurotrophic factor (GDNF) has been identified as a potent neurotrophic factor that enhances survival of midbrain dopaminergic neurons. GDNF is a glycosylated, disulfide-bonded homodimer. It promotes the survival and morphological differentiation of dopaminergic neurons and increases their high-affinity dopamine uptake. On the basis of these findings, it has been suggested that GDNF may play a role in the treatment of Parkinsonrsquo;s disease, which is marked by progressive degeneration of midbrain dopaminergic neurons./p