GDC-0879
Chemical Compounds
- 貨號 Cat. No.
- M1714
- 規格 Size
- 10mg,50mg,100mg
- 品牌 Brand
- No Brand
Description
GDC-0879 is a potent and selective B-Raf kinase inhibitor with an EC50 of 0.75 µM. GDC-0879 has been used in various research studies for its anti-cancer properties. In GDC-0879-treated mice, both cell line- and patient-derived BRAFV600E tumors exhibited stronger and more sustained pharmacodynamic inhibition (>90% for 8 hours) and improved survival compared with mutant KRAS–expressing tumors.
