GADD153 Antibody
- 貨號 Cat. No.
- 3421-100
- 規格 Size
- 100 µg
Description
pstrongAntibody Target :/strongGADD 153/p
pstrongHost: Rabbit /strong/p
pstrongAntibody Type: Polyclonal /strong/p
pstrongIsotype: Rabbit IgG /strong/p
pstrongAntibody Form: Affinity Purified Antibody /strong/p
pstrongImmunogen Sequence: Synthetic peptide surrounding amino acid 124 of human GADD153 /strong/p
pstrongAccession#: P35638 /strong/p
pstrongGene ID: 1649 /strong/p
pstrongAppearance: Colorless liquid /strong/p
pstrongConcentration: 0.2 mg/ml /strong/p
pstrongFormulation: 100 micro;g (0.2 mg/ml) Protein A purified rabbit polyclonal antibody in phosphate-buffered saline (PBS) containing 30% glycerol, 0.5% BSA, and 0.01% thimerosal. /strong/p
pstrongPurification: Affinity purified /strong/p
pstrongSpecies Reactivity: hu/ms/rt /strong/p
pstrongApplication: WB/IP/IHC /strong/p
pstrongApplication amp; Usage: Western blotting (0.5-4 micro;g/ml), immunoprecipitation (10-20 micro;g/ml), and immunohistochemistry (10-20 micro;g/ml). However, the optimal concentrations should be determined individually. The antibody recognizes 25 kDa GADD153 of human, mouse, and rat origins. /strong/p
pstrongStorage Temp.: -20 deg;C /strong/p
pstrongShipping : gel pack /strong/p
pstrongShelf Life: 12 months /strong/p
pstrongHandling: The antibody solution should be gently mixed before use. /strong/p
pstrongBrief Background Descriptions: GADD153 has been described as a growth arrest and DNA damage-inducible gene that encodes a C/EBP-related nuclear protein. Expression of GADD153 is induced by a variety of cellular stresses, including nutrient deprivation and metabolic perturbations. GADD153 functions to block cells in G1 to S phase in cell cycle progression and acts by dimerizing with other C/EBP proteins to direct GADD153 dimers away from ldquo;classicalrdquo; C/EBP binding sites. Thus GADD153 acts as a negative modulator of C/EBP-like proteins in certain terminally differentiated cells. /strong/p
pstrongHost: Rabbit /strong/p
pstrongAntibody Type: Polyclonal /strong/p
pstrongIsotype: Rabbit IgG /strong/p
pstrongAntibody Form: Affinity Purified Antibody /strong/p
pstrongImmunogen Sequence: Synthetic peptide surrounding amino acid 124 of human GADD153 /strong/p
pstrongAccession#: P35638 /strong/p
pstrongGene ID: 1649 /strong/p
pstrongAppearance: Colorless liquid /strong/p
pstrongConcentration: 0.2 mg/ml /strong/p
pstrongFormulation: 100 micro;g (0.2 mg/ml) Protein A purified rabbit polyclonal antibody in phosphate-buffered saline (PBS) containing 30% glycerol, 0.5% BSA, and 0.01% thimerosal. /strong/p
pstrongPurification: Affinity purified /strong/p
pstrongSpecies Reactivity: hu/ms/rt /strong/p
pstrongApplication: WB/IP/IHC /strong/p
pstrongApplication amp; Usage: Western blotting (0.5-4 micro;g/ml), immunoprecipitation (10-20 micro;g/ml), and immunohistochemistry (10-20 micro;g/ml). However, the optimal concentrations should be determined individually. The antibody recognizes 25 kDa GADD153 of human, mouse, and rat origins. /strong/p
pstrongStorage Temp.: -20 deg;C /strong/p
pstrongShipping : gel pack /strong/p
pstrongShelf Life: 12 months /strong/p
pstrongHandling: The antibody solution should be gently mixed before use. /strong/p
pstrongBrief Background Descriptions: GADD153 has been described as a growth arrest and DNA damage-inducible gene that encodes a C/EBP-related nuclear protein. Expression of GADD153 is induced by a variety of cellular stresses, including nutrient deprivation and metabolic perturbations. GADD153 functions to block cells in G1 to S phase in cell cycle progression and acts by dimerizing with other C/EBP proteins to direct GADD153 dimers away from ldquo;classicalrdquo; C/EBP binding sites. Thus GADD153 acts as a negative modulator of C/EBP-like proteins in certain terminally differentiated cells. /strong/p