G418 Sulfate (siRNA Vector Approved)

Alternate Name/Synonyms: Antibiotic G418

Appearance: White to off-white solid

Formulation: N/A

CAS Number: 108321-42-2

Molecular Formula: C₂₀H₄₀N₄O₁₀. 2 H₂SO₄

Molecular Weight: 692.71

Purity: ≥98%

Solubility: Hâ‚‚O (50 mg/ml)

Storage Temp.: RT

Shipping Conditions: RT

Description: Aminoglycoside antibiotic related to gentamycin that inhibits prokaryotic and eukaryotic protein synthesis. Toxic to bacteria, yeast, protozoans, helminths, higher plant, and mammalian cells. Widely used in the selection of eukaryotic expression vectors carrying the bacterial neor/kanr genes. The product of these genes, aminoglycoside 3′-phosphotransferase, inactivates G418, neomycin, and kanamycin by phosphorylation. Introduction of either of these genes into cells can confer resistance to G418, which enables cells to grow in media containing G418.

Handling: Protect from light and moisture