G3BP-1 (D226) Antibody
- 貨號 Cat. No.
- BS1132
- 規格 Size
- 100μg
- 品牌 Brand
- Bioworld
Description
stock
Host: Rabbit
Reactivity: Human,Mouse
Product
1 mg/ml in Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.2.
Purification & Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Specificity
G3BP-1 (D226) antibody detects endogenous levels of G3BP-1 protein.
Applications (Recommended Dilutions)
WB: 1:500~1:1000 IHC: 1:50~1:200
Western Blot(WB)
Western blot (WB) analysis of G3BP-1 (D226) antibody in extracts from COLO 205 cells.
Immunohistochemistry (IHC)
ImmunImmunohistochemistry (IHC) analyzes of G3BP-1 (D226) antibody in paraffin-embedded human lymphomatissue.ohistochemistry (IHC) analyzes of G3BP-1 (D226) antibody in paraffin-embedded human lymphomatissue.
Storage&Stability
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Background
G3BP is one of the DNA-unwinding enzymes which prefers partially unwound 3'-tailed substrates and can also unwind partial RNA/DNA and RNA/RNA duplexes in an ATP-dependent fashion. This enzyme is a member of the heterogeneous nuclear RNA-binding proteins and is also an element of the Ras signal transduction pathway. It binds specifically to the Ras-GTPase-activating protein by associating with its SH3 domain. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.
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