Forskolin
- 貨號 Cat. No.
- F-500
- 規格 Size
- 10 x 1 mg 10mg 25mg 50mg
Description
Forskolin
Adenylate Cyclase Activator
| Product#: | F-500 |
| Sizes: |
| 10 x 1 mg |
| 10 mg |
| 25 mg |
| 50 mg |
| M.W.: | 410.5 |
| CAS No.: | [66575-29-9] |
| Structure: |
| . |
 |
| Purity: | Greater than >98%. |
| Bioassay: |
The biological activity was tested to confirm the ability of Forskolin to activate (in vivo) adenylate cyclase in NIH/C6 neuroblastoma cells. |
 |
NIH/C6 cells were pre-incubated for 30 min with IBMX (10 mM), |
| References: |
1. | De Souza, N.J. (1993) J. Ethnopharmacol. 38, 177. |
2. | Insel, P.A. et al. (2003) Cell Mol. Neurobiol. 23, 305. |
3. | Hoffman, B.B. et al. (1987) Horm. Metab. Res. 19, 358. |
4. | Mills, I. et al. (1984) Endocrinology 115, 1066. |
5. | Christenson, J.T. et al. (1995) Vasa 24, 56. |
6. | Hermansen, K. (1985) Endocrinology. 116, 2251. |
7. | Metzger, H. et al. (1981) Arzneimittelforschung. 31, 1248. |
8. | Schlepper, M. et al. (1989) Basic Res. Cardiol. 84 Suppl 1, 197. |
9. | Hartzell, H.C. et al. (1992) Mol. Pharmacol. 41, 880. |
10. | Li, X. et al. (1995) Am. J. Physiol. 269, C986. |
Forskolin, is a cell permeable diterpenoid isolated from Coleus forskohlii. Forskolin has a unique ability to stimulate adenylate cyclase activity and increase cyclic adenosine monophosphate (cAMP).