Fluoro-Jade C (FJC) Powder for identifying Degenerating Neurons

ZZZZ_Status (Active, Disc) : Active

 

AA_Supplier Name : Biosensis

 

Alternative_Name (Other Names) :

FJC, Fluoro-Jade

 

Antibody_Isotype
(Antibody only) :

 

Application_Details :

Following our detailed protocol, Fluoro-Jade B labels degenerating neurons which are visualised with blue light excitation, while DAPI (not included) counter stains cell nuclei, visualised with ultra-violet illumination. The Fluoro-Jade C dye can be used on all kinds of preserved tissues, including fresh-frozen, paraformaldehyde or formalin fixed, and formalin fixed, paraffin-embedded tissues.

 

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(AB only, monoclonals) :

 

Datasheet_Link : https://www.biosensis.com/pdf_datasheet.php?products_id=1839

 

Description (Long Description) : 

The causes and effects of neuronal degeneration are of major interest to a wide variety of neuroscientists. Paralleling this growing interest is an increasing number of methods applicable to the detection of neuronal degeneration. Fluoro-Jade C stains all degenerating neurons regardless of specific insult or mechanism of cell death. Fluoro-Jade C exhibits the greatest signal to background ratio, as well as the highest resolution. This translates to a stain of maximal contrast and affinity for degenerating neurons. This makes it ideal for localising not only degenerating nerve cell bodies but also distal dendrites, axons and terminals. The dye is highly resistant to fading and is compatible with virtually all histological processing and staining protocols.

 

Expiry_Date : 

6 months after purchase if unopened.

 

Format (Form) : 

Dry, Coffee brown to brick red powder; hygroscopic powder keep dessicated.

 

Immunogen (Antigen) :

 

Kit_Components :

 

MSDS (File name) :https://www.biosensis.com/pdf_MSDS.php?products_id=1839