Fluoro-Jade B (FJB) Powder for identifying Degenerating Neurons

ZZZZ_Status (Active, Disc) : Active

 

AA_Supplier Name : Biosensis

 

Alternative_Name (Other Names) :

FJB, Fluoro-Jade

 

Antibody_Isotype
(Antibody only) :

 

Application_Details :

Following our detailed protocol, Fluoro-Jade C labels degenerating neurons which are visualised with blue light excitation, while DAPI (not included) counter stains cell nuclei, visualised with ultra-violet illumination. The Fluoro-Jade C dye can be used on all kinds of preserved tissues, including fresh-frozen, paraformaldehyde or formalin fixed, and formalin fixed, paraffin-embedded tissues.

 

Background_Info :

 

Clone_Name
(AB only, monoclonals) :

 

Datasheet_Link : https://www.biosensis.com/product_info.php/fluoro-jade-powder-identifying-degenerating-neurons-p-1840

 

Description (Long Description) : 

The fluorescent dye Fluoro-Jade® B (FJB), like its more purified brother Fluoro-Jade® C (FJ), is an anionic fluorescein derivative useful for the histological staining of neurons undergoing degeneration. Fluoro-Jade® B differs from FJC in that it is a slightly less refined chemical formulation and thus it does not quite provide the same level of signal to noise or high resolution as FJC. Nonetheless FJB is still widely used and works very well as a marker of degenerating neurons and even glia. [PMID: 17125750]. FJB operates nearly identically in protocol to that of FJC, and Fluoro-Jade® B is compatible with several other labeling procedures including immunofluorescent and fluorescent Nissl techniques. The powder is shipped at ambient temperature, see storage instructions for details.

 

Expiry_Date : 

6 months after purchase if unopened.

 

Format (Form) : 

Dry, Coffee brown to brick red powder; hygroscopic powder keep dessicated.

 

Immunogen (Antigen) :

 

Kit_Components :

 

MSDS (File name) :https://www.biosensis.com/pdf_MSDS.php?products_id=1840