Antibodies
Floxuridine
- 貨號 Cat. No.
- S1299
- 規格 Size
- 5~200mg
- 品牌 Brand
- Selleckchem
Description
Floxuridine
Catalog No.S1299
Floxuridine is a prodrugs of floxuridine and an oncology agent with an GI50 of 5.1 μM for the inhibition of MDCK/PEPT1.
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Distributor Tel: +886-2-2827-1197jimmy@new.abscience.com.tw
Biological Activity
Floxuridine (Fludara) is a prodrugs of floxuridine and an oncology agent with an GI50 of 5.1 μM for the inhibition of MDCK/PEPT1. Floxuridine (Fludara) belongs to the class known as antimetabolites. Floxuridine (Fludara) is most often used in the treatment of colorectal cancer. Floxuridine, an analog of 5-fluorouracil, is a fluorinated pyrimidine. Floxuridine (Fludara) works because it is broken down by the body into its active form, which is the same as a metabolite of 5-Fluorouracil. [1][2][3]
Chemical Information
| Molecular Weight (MW) | 246.19 |
|---|---|
| Formula | C9H11FN2O5 |
| CAS No. | 50-91-9 |
| Storage | 3 years -20℃Powder |
|---|---|
| 6 months-80℃in DMSO | |
| Syonnyms | Fluorodeoxyuridine, FUDR, FdUrd, Floxuridin, FAMP |
| Solubility (25°C) * | In vitro | DMSO | 49 mg/mL (199 mM) |
|---|---|---|---|
| Water | 49 mg/mL (199 mM) | ||
| Ethanol | 10 mg/mL (40 mM) | ||
| * <1 mg/ml means slightly soluble or insoluble. * Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. | |||
| Chemical Name | 5-fluoro-1-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)-tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione |
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Preparing Stock Solutions
| Stock Solution (1ml DMSO) | 1mM | 10mM | 20mM | 30mM |
|---|---|---|---|---|
| Mass(mg) | 0.24619 | 2.4619 | 4.9238 | 7.3857 |
