FKBP12 Antibody

貨號 Cat. No.
3635-100
規格 Size
100 µg

Description

pstrongAntibody Target :/strongFKBP 12/p
pbHost: /bRabbit/p
pbAntibody Type: /bPolyclonal/p
pbIsotype: /bRabbit IgG/p
pbAntibody Form: /bAffinity Purified Antibody/p
pbImmunogen Sequence: /bSynthetic peptide surrounding amino acid 10 of mouse FKBP12/p
pbAccession#: /bP26883/p
pbGene ID: /b14225/p
pbAppearance: /bColorless liquid/p
pbConcentration: /b0.5 mg/ml/p
pbFormulation: /b100 micro;g (0.5 mg/ml) in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 0.01% thimerosal./p
pbPurification: /bAffinity purified/p
pbSpecies Reactivity: /bhu/ms/rt/p
pbApplication: /bWP/IHC/IP/p
pbApplication amp; Usage: /bWestern blot (0.5-4 micro;g/ml), immunoprecipitation (2-10 micro;g/ml) and immunohistochemistry (2-10 micro;g/ml). However, the optimal conditions should be determined individually. The antibody detects 12 kDa FKBP12 protein in samples from human, mouse, and rat origins./p
pbStorage Temp.: /b-20 deg;C/p
pbShipping : /bgel pack/p
pbShelf Life: /b12 months/p
pbHandling: /bThe antibody solution should be gently mixed before use./p
pbBrief Background Descriptions: /bFKBP12 is a member of the family of soluble receptors capable of binding to one of two major immunosuppressant agents. FKBP12 also plays a role in intracellular calcium regulation by associating with three types of calcium release channel complexes, cardiac and skeletal ryanodine receptors and the inositol 1,4,5-trisphosphate receptor. In interactions with members of the TGF beta family type I receptors, FKBP12 has been shown to exert an inhibitory effect on the signaling pathway./p

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