FITC-Labeled Human BCMA / TNFRSF17 Protein, Fc Tag

Source : 

FITC-Labeled Human BCMA, Fc Tag (Cat. No. BCA-HF254) is expressed from human HEK293 cells. It contains AA Met 1 - Ala 54 (Accession # Q02223-1). It is the FITC labeled form of Human BCMA, Fc Tag (Cat. No. BC7-H5254).

 

Molecule : BCMA

 

Synonyms : TNFRSF17,CD269,BCM,BCMA

 

Format : Powder

 

Category : Fluorescent labeled protein

 

Accession : NP_001183.2

 

Storage : -20℃, aviod light

 

Shipping condition : Powder,RT, Avoid light

 

Molecular Weight : 32.0 kDa

 

Characteristics :

This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 32.0 kDa. As a result of glycosylation, the protein migrates as 35-44 kDa under reducing (R) condition, and 60-75 kDa under non-reducing (NR) condition (SDS-PAG

 

Endotoxin Level : Less than 1.0 EU per μg by the LAL method.

 

Buffer : PBS, pH7.4

 

Description :

Tumor necrosis factor receptor superfamily member 17 (TNFRSF17) is also known as B-cell maturation protein (BCMA), CD antigen CD269, which is a member of the TNF-receptor superfamily. TNFRSF17 contains one TNFR-Cys repeat. TNFRSF17 is expressed in mature B-cells, but not in T-cells or monocytes. TNFRSF17 is receptor for TNFSF13B/BLyS/BAFF and TNFSF13/APRIL. TNFRSF17 promotes B-cell survival and plays a role in the regulation of humoral immunity. TNFRSF17 can activate NF-kappa-B and JNK.

 

References :

(1) Hatzoglou A., et al., 2000, J. Immunol. 165:1322-1330.
(2) Gross J.A., et al., 2000, Nature 404:995-999.
(3) Yu G., et al., 2000, Nat. Immunol. 1:252-256.