Fingolimod (FTY-720A, FTY720)

Alternate Name/Synonyms: FTY-720A, FTY721

Appearance: White solid

Formulation: N/A

CAS Number: 162359-56-0

Molecular Formula: C₁₉H₃₃NO₂.HCl

Molecular Weight: 343.93

Purity: ≥98% by HPLC

Solubility: DMSO (100 mg/ml) of EtOH (100 mg/ml)

Storage Temp.: -20°C

Shipping Conditions: RT

Description: FTY720 can be phosphorylated by sphingosine kinase, which then acts as a potent agonist at four of the sphingosine-1-phosphate (S1P) receptors (S1P1, S1P3, S1P4, and S1P5). ICâ‚…â‚€ of (S)- and (R)- FTY720-phosphate on lymphocyte migration toward 10 nM of S1P are 0.137 nM and 10.98 nM respectively. The ICâ‚…â‚€ values to cell lines MCF-7 is 6.8±0.6 µM.

Handling: Protect from air and moisture