Fibronectin (A32) Antibody

h1 class=titleFibronectin (A32) Antibody/h1
div id=node-468 class=node ntype-antibodiesMouse Monoclonal
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h4Catalog Number/h4
pstrong250270/strong/p
h4Unit/h4
pstrong0.2 mg /strong/p
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pnbsp;/p
Format/h4
pEach vial contains 0.2 mg IgG in 0.2 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-A/G affinity chromatography./p
pnbsp;/p
h4Data and Images/h4
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h4Description/h4
pFibronectin is an adhesive glycoprotein with a molecular mass of 440 kDa. It is believed to be important for the formation of a provisional matrix that promotes cell adhesion and migration during wound healing. Its age-dependent increase in plasma and tissues may be accompanied in pathological states, especially in tumor growth, by its proteolytic breakdown by a number of neutral proteases. It has also shown that several of its proteolytic breakdown products exhibit unexpected and mostly harmful biological activities. This antibody is highly specific for fibronectin. There is no evidence for cross-reactivity with other connective tissue proteins (vitronectin, elastin, collagen, laminin This antibody reacts with human fibronectin. Other species have not been tested./p
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h4Product Citations/h4
pnbsp;/p
h4Recommended Products/h4
pa href=http://abbiotec.com/antibodies/fibronectin-%28a22%29-antibody250269 Fibronectin (A22) Antibody/abr /
a href=http://abbiotec.com/antibodies/fibronectin-%28a17%29-antibody250268 Fibronectin (A17) Antibody/abr /
a href=http://abbiotec.com/antibodies/fibronectin-%28a35%29-antibody250271 Fibronectin (A35) Antibody/abr /
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h4Alternate Names/h4
pFN;nbsp; Cold-insoluble globulin;nbsp; CIG/p
h4Accession No./h4
pa class=accession-link target=_blank href=http://www.expasy.org/uniprot/P02751P02751/abr /
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h4Clonality/h4
pA32/p
h4Antigen/h4
pnbsp;/p
pBovine corneal endothelial cells/p
pnbsp;/p
h4Application Notes/h4
pnbsp;/p
pProduct Cat. No. 250270 can be used in ELISA, Western blotting, immunoprecipitation and immunostaining of frozen PLP-fixed sections of bovine and human tissues. The antibody inhibits cell adhesion to fibronectin mediated by the heparin-binding domain. It can be used to probe fibronectin conformation and to quantitate plasma fibronectin in a sandwich ELISA with antibody Product Cat. No. 250271./p
pE: 1:4,000;/p
pWB: 1:100;/p
pIHC: 1:200/p
pIP:Use at an assay dependent concentration/p
pstrongReacts with/strongnbsp; :H | Other/p
pnbsp;/p
h4Storage/h4
pStore at 4deg;C. Product is guaranteed 6 months from the date of shipment./p
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