Fibrinogen (2F4) Antibody

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h1 class=titleFibrinogen (2F4) Antibody/h1
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h4Catalog Number/h4
pstrong250312/strong/p
h4Unit/h4
pstrong0.2 mg /strong/p
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Format/h4
pEach vial contains 0.2 mg IgG in 0.2 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-A/G affinity chromatography./p
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h4Description/h4
pFibrinogen, the precursor of fibrin, is the coagulable protein in the blood plasma of vertebrates. Fibrinogen consists as a dimer of 3 pairs of non-identical chains Aa (Mr= 66,800), Bb (Mr= 52,000) and g (Mr=46,500) cross-linked by disulfide bonds in their N-terminal segments. The molecule has 2 terminal D domains and one central E domain, all three domains are separated when fibrinogen is degradated by plasmin. MW is 340 kDa. Concentration in human plasma is 2-3 mg/ml. This antibody has specificity for human fibrinogen degradation product D-fragment. The antibody reacts with both purified D-monomer, fibrinogen and factor VIII./p
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h4Product Citations/h4
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h4Recommended Products/h4
pa href=http://abbiotec.com/antibodies/fibrinogen-%281d6%29-antibody250310 Fibrinogen (1D6) Antibody/abr /
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h4Alternate Names/h4
pFibrinogen alpha chain; FGA/p
h4Accession No./h4
pa class=accession-link target=_blank href=http://www.expasy.org/uniprot/P02671P02671/abr /
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h4Clonality/h4
p2F4/p
h4Antigen/h4
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pFibrinogen isolated from human plasma/p
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h4Application Notes/h4
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pProduct Cat. No. 250312 reacts strongly with D-monomer in ELISA with antigen directly coated onto the microtiter plate or in sandwich ELISA in combination with a polyclonal antibody against fibrinogen. Product Cat. No. 250312 reacts in western blot with fibrinogen degradation product D-monomer in non-reduced forms (92 kDa)./p
pE: 1:16,000;/p
pWB: 1:2,000/p
pstrongReacts with/strongnbsp; :H/p
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h4Storage/h4
pStore at 4deg;C. Product is guaranteed 6 months from the date of shipment./p
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