Proteins and Peptides
FAS / CD95 Antibody (LS-B2820)
- 貨號 Cat. No.
- LS-B2820
- 規格 Size
- 50 µg
- 品牌 Brand
- LSBio
Description
| Antibody Catalog ID: | LS-B2820 |
|---|---|
| Antibody Validation: | This antibody replaces catalog number LS-C46014. It has been validated for use in the following assays: IHC-P. |
| Antibody Target: | FAS / CD95 |
| Synonyms: | FAS, ALPS1A, APO-1, apo11 antigen, apoptosis antigen 1, apoptosis-mediating surface antigen fas, apt1, CD95, cd95 antigen, FAS1, fasl receptor, fasl receptors, FASTM, tnfrsf6 |
| Family: | TNF Receptor |
| Subfamily: | not assigned-TNF Receptor |
| Host: | FAS antibody was produced in Mouse |
| Antigen Species: | FAS antibody was raised against Human |
| Clonality: | Monoclonal |
| Isotype: | IgG1 |
| Antibody Clone Name: | LT95 |
| Antigen Type: | Cells |
| Immunogen: | FAS antibody was raised against hUT-78 human T cell lymphoma cell line |
| Antibody Specificity: | Reacts with CD95 (Fas/APO-1), a 46 kD single chain type I glycoprotein of the tumor necrosis factor/nerve growth factor (TNF/NGF) receptor superfamily, expressed on a variety of normal and neoplastic cells. It seems that the antibody LT95 does not induce Fas mediated apoptosis, although it cross-blocks anti-Fas DX2 antibody that recognizes a functional epitope of Fas molecule. |
| Purification: | Ion Exchange Chromatography |
| Presentation: | 20 mM Tris/HCl, 15 mM sodium azide, approx., pH 7.4. |
| Recommended Storage: | +4°C or -20°C, Avoid repeated freezing and thawing. |
| Antibody Usage Summary: | Immunohistochemistry: LS-B2820 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody LS-D2, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for LS-B2820 was determined to be 10 ug/ml. |
| Antibody Uses: | Immunohistochemistry - Paraffin (IHC-P) (10 µg/ml), Flow Cytometry (Flo) (Optimal dilution to be determined by the researcher) |
| Size: | 50 µg |
| Concentration: | 1 mg/ml |
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