Fas/Apo1/CD95 Polyclonal Ab
- 貨號 Cat. No.
- 3070-100
- 規格 Size
- 100 ug
Description
pfont size=2strongHOST:/strong Rabbitbr /
br /
strongIMMUNOGEN: /strongSynthetic peptide corresponding to residues surrounding amino acid 32 of mouse Fas.br /
br /
/fontfont size=2strongFORMULATION: br /
/strong100 ug (0.2 mg/ml) immunoaffinity purified, rabbit anti-Fas polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 50% glycerol, 1% BSA, 0.02% thimerosal.br /
br /
strongSPECIES:/strong human, mouse, rat, monkey, sheep, rabbit, pig, bovine and hamsterbr /
br /
/fontfont size=2strongSTORAGE CONDITIONS: br /
/strongStore at -20oC. For long-term storage, aliquot and freeze at -70oC. Avoid repeated freeze/defrost cycles.br /
br /
/fontfont size=2strongBACKGROUND DESCRIPTION: br /
/strongFas/Apo-1/CD95 is a cell surface type-I membrane glycoprotein with an apparent molecular weight of 44 kDa on SDS-PAGE. Fas is a member of the TNFR family that includes TNFR1, TNFR2, CD27, CD30, and CD40. Binding of Fas-ligand (FasL) to Fas or crosslinking of Fas by anti-Fas monoclonal antibodies leads to apoptosis in Fas expressing cells. Both Fas and TNF-R contain the 70 amino acids cytoplasmic quot;death domainquot; that is responsible for transmitting signal for apoptosis.br /
br /
/fontfont size=2strongSPECIFICITY:br /
/strongDetects a 44 kDa Fas on SDS-PAGE immunoblots. A minor 31 kDa band can also be detected in certain cell lines. Cell lines have been tested include K562, A431, HeLa, Jurkat, MCF-7, CHO, MDCK, MOLT-4, Hs67, RAW264, MDBK, MDOK, etc. br /
/fontstrongbr /
font size=2APPLICATION AND USAGE: br /
/font/strongfont size=2The antibody can be used for Western blotting (1-4 ug/ml). However, the optimal conditions should be determined individually.br /
br /
/fontstrongfont size=2FOR RESEARCH USE ONLY! Not to be used in humans./fontbr /
/strong/p
br /
strongIMMUNOGEN: /strongSynthetic peptide corresponding to residues surrounding amino acid 32 of mouse Fas.br /
br /
/fontfont size=2strongFORMULATION: br /
/strong100 ug (0.2 mg/ml) immunoaffinity purified, rabbit anti-Fas polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 50% glycerol, 1% BSA, 0.02% thimerosal.br /
br /
strongSPECIES:/strong human, mouse, rat, monkey, sheep, rabbit, pig, bovine and hamsterbr /
br /
/fontfont size=2strongSTORAGE CONDITIONS: br /
/strongStore at -20oC. For long-term storage, aliquot and freeze at -70oC. Avoid repeated freeze/defrost cycles.br /
br /
/fontfont size=2strongBACKGROUND DESCRIPTION: br /
/strongFas/Apo-1/CD95 is a cell surface type-I membrane glycoprotein with an apparent molecular weight of 44 kDa on SDS-PAGE. Fas is a member of the TNFR family that includes TNFR1, TNFR2, CD27, CD30, and CD40. Binding of Fas-ligand (FasL) to Fas or crosslinking of Fas by anti-Fas monoclonal antibodies leads to apoptosis in Fas expressing cells. Both Fas and TNF-R contain the 70 amino acids cytoplasmic quot;death domainquot; that is responsible for transmitting signal for apoptosis.br /
br /
/fontfont size=2strongSPECIFICITY:br /
/strongDetects a 44 kDa Fas on SDS-PAGE immunoblots. A minor 31 kDa band can also be detected in certain cell lines. Cell lines have been tested include K562, A431, HeLa, Jurkat, MCF-7, CHO, MDCK, MOLT-4, Hs67, RAW264, MDBK, MDOK, etc. br /
/fontstrongbr /
font size=2APPLICATION AND USAGE: br /
/font/strongfont size=2The antibody can be used for Western blotting (1-4 ug/ml). However, the optimal conditions should be determined individually.br /
br /
/fontstrongfont size=2FOR RESEARCH USE ONLY! Not to be used in humans./fontbr /
/strong/p