Factor B Caiman (11-B28) Antibody

h1 class=titleFactor B Caiman (11-B28) Antibody/h1
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h4Catalog Number/h4
pstrong250444/strong/p
h4Unit/h4
pstrong0.2 mg /strong/p
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Format/h4
pEach vial contains 0.2 mg IgG in 0.2 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-A/G affinity chromatography./p
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h4Description/h4
pComplement factor B plays an imortant role in the alternative complement activation pathway by complexing with C3b to create the active C3 convertase. The alternative activation pathway was the first to evolve, thus the components involved are very similar in physological different species. The caiman complement factor B is similar to the mammalian counterpart and consists of a single polypeptide chain of approximately 90 kDa which upon activation is cleaved in a Ba fragment (60 kDa) and a Bb fragment (30 kDa). This antibody reacts with unactivated caiman complement factor B and the Bb fragment of activated factor B./p
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h4Product Citations/h4
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h4Recommended Products/h4
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h4Alternate Names/h4
pC3/C5 convertase;nbsp; Properdin factor B;nbsp; Glycine-rich beta glycoprotein;nbsp; GBG;nbsp; PBF2/p
h4Accession No./h4
pa class=accession-link target=_blank href=http://www.expasy.org/uniprot/P00751P00751/abr /
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h4Clonality/h4
p11-B28/p
h4Antigen/h4
pnbsp;/p
pRecombinant von Willebrandt domain of caiman factor B/p
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h4Application Notes/h4
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pProduct Cat. No. 250444 reacts with caiman factor B in western blot, immunoprecipitation, and affinity purificatin. In ELISA however Product Cat. No. 250444 reacts with native caiman factor Bb or intact factor B. Caiman plasma can inhibit binding of the antibody to recombinant immunogen coated in microplate./p
pE: 1:5,000/p
pWB: 1:500/p
pstrongReacts with/strongnbsp; :Other/p
pnbsp;/p
h4Storage/h4
pStore at 4deg;C. Product is guaranteed 6 months from the date of shipment./p
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