Factor B (9B8) Antibody

h1 class=titleFactor B (9B8) Antibody/h1
div id=node-490 class=node ntype-antibodiesMouse Monoclonal
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h4Catalog Number/h4
pstrong250291/strong/p
h4Unit/h4
pstrong0.2 mg /strong/p
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pnbsp;/p
Format/h4
pEach vial contains 0.2 mg IgG in 0.2 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-A/G affinity chromatography./p
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h4Description/h4
pFactor B is a component of the alternative pathway of complement activation. The protein consists of a single polypeptide chain of molecular mass 93 kDa, and has a concentration in plasma of approximately 200 ,mg/mL. Factor B is cleaved by factor D into the Ba component (30 kDa) and the Bb (63 kDa). Together with C3b, Bb forms the alternative pathway C3 convertase C3bBb. This antibody is specific for the Bb fragment of human factor B. Antibody binding abolishes the formation of C3bBb complexes./p
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h4Product Citations/h4
pnbsp;/p
h4Recommended Products/h4
pa href=http://abbiotec.com/antibodies/factor-b-%286g11-%29-antibody250293 Factor B (6G11 ) Antibody/abr /
a href=http://abbiotec.com/antibodies/factor-b-%289b6%29-antibody250292 Factor B (9B6) Antibody/abr /
nbsp;/p
h4Alternate Names/h4
pC3/C5 convertase;nbsp; Properdin factor B;nbsp; Glycine-rich beta glycoprotein;nbsp; GBG;nbsp; PBF2/p
h4Accession No./h4
pa class=accession-link target=_blank href=http://www.expasy.org/uniprot/P00751P00751/abr /
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h4Clonality/h4
p9B8/p
h4Antigen/h4
pnbsp;/p
pComplemen factor B purified from human plasma and adsorbed to aluminum hydroxide gel/p
pnbsp;/p
h4Application Notes/h4
pnbsp;/p
pProduct Cat. No. 250291 reacts strongly with human factor B. Strong reaction is seen when used as detection antibody in sandwich ELISA with a polyclonal capture antibody against factor B. In Western blot, Product Cat. No. 250291 reacts with the Bb fragment of factor B in its non-reduced form only. Product Cat. No. 250291 can be used for the affinity purification of human factor B when coupled to a suitable matrix./p
pE: 1:13,000;/p
pWB: 1:1,000/p
pstrongReacts with/strongnbsp; :H/p
pnbsp;/p
h4Storage/h4
pStore at 4deg;C. Product is guaranteed 6 months from the date of shipment./p
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